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2019 Sep 4;36(Suppl 2):4758

mGluR5 acts as an important cofactor, its chronic activation can enhance NMDA receptors (NMDARs) activity and further amplify neuronal excitotoxicity [37]

doi: 10.1042/BST20140078 220

Why growth hormone matters Growth hormone production peaks during adolescence and young adulthood, then declines approximately 15% per decade after age 30